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M94A2441.TXT
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1994-10-25
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Document 2441
DOCN M94A2441
TI Slow-down of HIV epidemic among IDUs in Geneva, Switzerland.
DT 9412
AU Broers B; Junet C; Gabriel V; Perrin L; Hirschel B; Infectious Diseases,
University Hospital, Geneva.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):303 (abstract no. PC0141). Unique
Identifier : AIDSLINE ICA10/94370134
AB OBJECTIVE: 36% of AIDS in Geneva are intravenous drug users (IDUs).
Preventive strategies: syringe exchange, methadone, free condoms. How
does the HIV-epidemic evolve in IDUs since institution of these
measures? METHODS: Data from: 1) Geneva part of the Swiss HIV Cohort
Study, with 6-monthly follow-ups 2) Geneva Methadone Cohort Study, with
more than 500 IDU enrolled since February 1988 and tested for HIV every
6 months. RESULTS: Comparing 1993 and 1991: decrease in newly discovered
cases of HIV infection (-61%), of AIDS cases (-49%), death from AIDS
(-26%). Increase in average age at start of follow up from 28.9 years in
1988 to 31.8 in 1993, decrease in average CD4 count at start of follow
up (suggesting that newly discovered infections occurred a long time
ago). Seroprevalence of 8% among those starting methadone treatment in
1992-93 versus 51% in 1984-85. Seroconversion of 0.95% per person year
of follow up from 1988 to 1993, compared to > 10% between 1981 and 1983.
CONCLUSIONS: Epidemiologic indicators of HIV infection consistently show
a slow-down of the HIV epidemic among IDU in Geneva. It is important to
continue and adjust existing harm-reduction strategies.
DE Adult Cohort Studies Human HIV
Infections/COMPLICATIONS/*EPIDEMIOLOGY/PREVENTION & CONTROL HIV
Seroprevalence Substance Abuse, Intravenous/*COMPLICATIONS
Switzerland/EPIDEMIOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).